Mack Reynolds

IMMUNOLOGY PROGRAM GRADUATE STUDENT PRE-CANDIDATE

Biography

Mack graduated from the University of California at Davis in 2017 with a B.S. in biochemistry. At UC Davis, he worked as an undergraduate researcher in Dr. Scott Simon’s lab studying innate immune cell trafficking in a mouse model of Staphylococcus aureus skin and soft tissue infection. Following graduation, Mack worked in the same lab developing a microfluidic device to predict susceptibility to atherosclerosis in a clinical setting. Mack is now a Ph.D. student in the Program in Immunology at the University of Michigan working in the lab of Dr. Mary O’Riordan.

Research Interests

Mack is studying the role of mitochondrial stress in innate immune responses to bacterial infection.

Abstracts

Autumn Immunology Conference, November 2018 Reynolds MB, He X, Xu J, Gao X, Toffaletti D, Ivey M, Kolbe J, Lopez R, Mechler C, Perfect J, Olszewski M Trehalose-6-phosphate synthase-deletion in Cryptococcus neoformans elicits rapid innate fungal clearance from the lungs with early neutrophil accumulation.

Publications

Falahee PC, Anderson LS, Reynolds MB, Pirir M, McLaughlin BE, Dillen CA, Cheung AL, Miller LS, Simon SI. (2017). α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in Staphylococcus aureus-Infected Wounds. J Immunol. 199(5) doi: 10.4049/jimmunol.1700649.

Anderson LS, Yu S, Rivara KR, Reynolds MB, Hernandez AA, Wu X, Yang HY, Isseroff RR, Miller LS, Hwang ST, Simon SI. (2019). CCR6+ γδ T cells home to skin wounds and restore normal wound healing in CCR6-deficient mice. J Invest Dermatol. doi: 10.1016/j.jid.2019.02.032.

Anderson LS, Reynolds MB, Rivara KR, Miller LS, Simon SI. (2019). A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection. J Vis Exp. doi: 10.3791/59015.

Immunology Mentor