Emily Yarosz

IMMUNOLOGY PROGRAM GRADUATE STUDENT CANDIDATE

Biography

Emily graduated from the Pennsylvania State University in 2016 with a B.S. in Immunology and Infectious Disease. While at PSU, she worked in the lab of Dr. Robert Paulson as an undergraduate researcher studying hematopoietic cell development and stress erythropoeisis. Emily entered the Graduate Program in Immunology in the Fall of 2016, and she later joined the lab of Dr. Cheong-Hee Chang for her thesis work. When she's not in the lab, Emily loves to bake, read, and explore downtown Ann Arbor with friends.
 

 

Research Interests

Cellular metabolism has been shown to play a critical role in regulating the responses of various immune cells to infection. As such, our lab aims to better understand how different metabolic pathways drive adaptive immune responses to infectious disease and autoimmunity. My thesis work focuses on understanding how the E3 ubiquitin ligase Cullin 3 (Cul3) interacts with intracellular metabolic processes to influence the proliferation, activation, and development of effector functions in both CD4 T cells and NKT cells.

Techniques

T cell-specific murine models, Tamoxifen-inducible Cre-ERT2 system, Flow Cytometry, FACS, Western Blot, qPCR

Awards

AAI Young Investigator Award, Autumn Immunology Conference 2018

Abstracts

1. Yarosz, E.L., Ye, C., Kumar, A., and C.H. Chang. Novel roles for Cullin 3 in modulating CD4 T cell-mediated immune responses. University of Michigan Graduate Program in Immunology Annual Retreat. Oregon, OH. June 2019. Oral Presentation.

2. Yarosz, E.L. and C.H. Chang. Understanding the role of Cullin 3 in NKT cell peripheral maintenance. Autumn Immunology Conference. Chicago, IL. November 2018. Oral and Poster Presentations.

3. Yarosz, E.L., Kumar, A., Ye, C., Seo, Y.A., and C.H. Chang. Iron as an essential regulator of CD4 T cell proliferation and function. University of Michigan Microbiology and Immunology Departmental Retreat. Hickory Corners, MI. October 2018. Poster Presentation.

Publications

Immunology Mentor