1. Role of TET2 and/or DNMT3A in CD4+ T cell differentiation
2. Epigenetic regulation of memory vs. effector CD8+ T cell differentiation
3. Cooperation of co-occurring PTCL mutations with TET2 loss in T cell transformation
Lung immunity in humans and mice.
Specifically: immunopathogenesis of COPD; Efferocytosis; Interactions of lung leukocytes with the lung microbiome.