1. Role of TET2 and/or DNMT3A in CD4+ T cell differentiation
2. Epigenetic regulation of memory vs. effector CD8+ T cell differentiation
3. Cooperation of co-occurring PTCL mutations with TET2 loss in T cell transformation
Fundamental molecular mechanisms and cell biology of T lymphocyte activation. Advanced molecular imaging using light and electron microscopy. Focus on innate-like T cells, directed cellular immunotherapies, and HIV/T cell interactions
Lung immunity in humans and mice.
Specifically: immunopathogenesis of COPD; Efferocytosis; Interactions of lung leukocytes with the lung microbiome.