Faculty

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(Includes Name, Title, Research Interests, Techniques)

Bethany Moore, PhD

Galen B. Toews, MD Collegiate Professor of Pulmonary and Critical Care Medicine
Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
Professor of Microbiology and Immunology
Director Graduate Program in Immunology
bmoore@umich.edu
Accepting Students
Research Interests:

Chemokine, cytokine and eicosanoid regulation of pulmonary fibrosis; pulmonary infections post bone-marrow transplant

Ulus Atasoy, M.D., M.A.

Associate Professor, Department of Internal Medicine, Division of Allergy and Clinical Immunology
Chief of Allergy-Immunology, Ann Arbor VA
atasoyu@med.umich.edu
Research Interests:

- Posttranscriptional gene regulation in lung inflammation and cancer - RNA biology - Asthma and allergy - The role of the RNA binding protein HuR in 1) allergen induced airway inflammation, and 2) helper T cell differentiation and function

Challice Bonifant, MD, PhD

Assistant Professor, Department of Pediatrics and Communicable Diseases
Division of Hematology/Oncology
challice@umich.edu
Accepting Students
Research Interests:
The primary focus of our laboratory is the development and study of immunotherapies designed to treat Acute Myeloid Leukemia.
 

Shannon Carty, MD

Assistant Professor of Internal Medicine, Division of Hematology/Oncology
scarty@umich.edu
Accepting Students
Research Interests:

1. Role of TET2 and/or DNMT3A in CD4+ T cell differentiation

2. Epigenetic regulation of memory vs. effector CD8+ T cell differentiation

3. Cooperation of co-occurring PTCL mutations with TET2 loss in T cell transformation

Marilia Cascalho, M.D., Ph.D.

Associate Professor of Surgery, Microbiology & Immunology
marilia@umich.edu
Accepting Students
Research Interests:

B cell memory, B cell and immunoglobulin dependent T cell development and function and generation of diversity in health and disease

Maria Castro, Ph.D.

R.C. Schneider Collegiate Professor of Neurosurgery
Professor of Cell and Developmental Biology
mariacas@umich.edu
Accepting Students
Research Interests:
Pediatric and adult brain cancer biology and therapeutics. Epigenetics, cancer metabolism, and signaling networks that mediate tumor progression. Uncovering the role of secreted cancer ligands in hematopoietic stem cell development and anti-tumor immunity. Nanotechnology to develop novel anti-cancer therapies. DNA damage, DNA damage response,
...

Cheong-Hee Chang, Ph.D.

Professor of Microbiology and Immunology
heechang@umich.edu
Accepting Students
Research Interests:

Regulation of innate-like CD4 T cell development and function

Grace Chen, M.D., Ph.D.

Associate Professor of Internal Medicine, Division of Hematology/Oncology
gchenry@umich.edu
Accepting Students
Research Interests:

Inflammation and cancer; role of gut microbiota and Nod-like receptors in colitis and cancer

Stephen Chensue, M.D., Ph.D.

Professor of Pathology
Chief, Pathology and Laboratory Medicine, Veteran Affairs
schensue@umich.edu
Research Interests:

Cellular and molecular mechanisms of leukocyte mobilization during granulomatous formation; pathology

Kathleen Collins, M.D., Ph.D.

Professor of Internal Medicine
Professor of Microbiology and Immunology
klcollin@umich.edu
Accepting Students
Research Interests:
The Collins lab focuses on understanding the molecular mechanisms by which virally infected cells establish a persistent infection; we use patient samples to determine which cells form clinically significant reservoirs and to develop strategies to eradicate them. A major focus of the Collins laboratory has been on understanding the role of
...

Jeffrey Curtis, M.D.

Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
jlcurtis@umich.edu
Accepting Students
Research Interests:

Lung immunity in humans and mice. 
Specifically: immunopathogenesis of COPD; Efferocytosis; Interactions of lung leukocytes with the lung microbiome. 

David Fox, M.D.

Professor, Department of Internal Medicine
Chief, Division of Rheumatology
dfox@umich.edu
Research Interests:

Human T lymphocyte biology, rheumatoid arthritis, T cell interactions with synovial cells, regulation of TH17 cells

Luigi Franchi, MD, PhD

Assistant Professor of Pediatrics and Communicable Diseases, Hematology/Oncology
luigif@med.umich.edu
Research Interests:
The understanding that the immune system protects us not only from infections but also from cancer has led to the development of therapeutic approaches which boost the activity of the immune system against established tumors.
...

Christine Freeman, PhD

Research Assistant Professor, Internal Medicine, Division of Pulmonary and Critical Care Medicine
cmfreema@umich.edu
Research Interests:

Role of Toll-like receptors on CD8+ and CD4+ T cells and NK cells in regards to chronic obstructive pulmonary disease; Immunopathogenesis of chronic obstructive pulmonary disease. 

Katherine Gallagher, MD

Associate Professor of Surgery, Section of Vascular Surgery
Co-Director, Multidisciplinary PAD program
kgallag@umich.edu
Accepting Students
Research Interests:

Dr. Gallagher's lab investigates the role of bone marrow stem cells in diabetic wound healing and peripheral artery disease (PAD).

Daniel Goldstein, MD

Eliza Maria Mosher Collegiate Professor in Internal Medicine
Research Professor, Institute of Gerontology
Director, Michigan Biology of Cardiovascular Aging
drgoldst@umich.edu
Accepting Students
Research Interests:

The overall theme of Dr. Goldstein’s laboratory is how inflammation impacts different disease states. Broadly, Dr. Goldstein’s laboratory investigates the importance of inflammation in organ transplantation, and in aging

Irina Grigorova, Ph.D.

Assistant Professor of Microbiology and Immunology
igrigor@umich.edu
Accepting Students
Research Interests:

Regulation and control of humoral (antibody) immune response; intravital imaging and quantitative analysis of lymphocyte dynamic behavior in living
mice.

Johann Gudjonsson, M.D., Ph.D.

Associate Professor of Dermatology
johanng@med.umich.edu
Accepting Students
Research Interests:
Immunology, genetics, bioinformatics
 

Joseph Holoshitz, M.D.

Professor of Internal Medicine, Division of Rheumatology
Associate Chief for Research
jholo@umich.edu
Accepting Students
Research Interests:

Signal transduction, small molecules and immunomodulatory peptides in autoimmunity; Gene-environment interaction in autoimmunity;Molecular mechanisms of MHC-disease association

Gary Huffnagle, Ph.D.

Nina and Jerry D Luptak Professor
Research Professor, Mary H Weiser Food Allergy Center
Professor, Department of Internal Medicine, Pulmonary & Critical Care Medicine
Professor, Department of Molecular, Cellular and Developmental Biology
Professor, Department of Microbiology and Immunology
ghuff@umich.edu
Accepting Students
Research Interests:

Pulmonary immunology; fungal pathogenesis and microflora-mediated modulation of immunity

David Irani, M.D.

Associate Professor of Neurology, Holtom-Garrett Program in Neuroimmunology
davidira@umich.edu
Research Interests:

Neuroimmunology; immunopathogenesis of viral infections of the central nervous system; innate immunity to viruses; immune mechanisms of neuronal and glial cell injury

J. Michelle Kahlenberg, M.D., Ph.D.

Assistant Professor of Internal Medicine, Division of Rheumatology
mkahlenb@umich.edu
Accepting Students
Research Interests:

The interplay between innate immunity and autoimmune disease development. Specifically, I am interested in the cross-talk between dermal and systemic inflammation and how this may influence disease development.

Nobuhiko Kamada, Ph.D.

Assistant Professor of Internal Medicine, Division of Gastroenterology
nkamada@med.umich.edu
Research Interests:

Mucosal Immunology in gastrointestinal tract: host-microbial interaction in the pathogenesis of inflammatory bowel disease.

Venkat Keshamouni, Ph.D.

Associate Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
vkeshamo@umich.edu
Research Interests:

Cancer cell and host immune cell interactions in tumor microenvironment; Tumor tolerance mechanisms; TGF-b and TLR signaling

Chang Kim, PhD

Professor of Pathology
Kenneth and Judy Betz Family Endowed Professor
Mary H. Weiser Food Allergy Center
Experimental Pathology, Department of Pathology
chhkim@med.umich.edu
Accepting Students
Research Interests:

Mucosal immunology, inflammation, and cancer
Migration of innate immune cells and lymphocytes
Development of T cells (FoxP3+, Tr1, andTh17 cells) and dendritic cells in health and disease Roles of vitamin A and retinoic acid in regulation of the immune system
Roles of microbial metabolites (short chain fatty acids) in regulation of the immune system
Roles of hormones in regulation of the immune system
Regulation of Tfh, GC-T cells, and B cell antibody production
Gut Microbiota and Immune Responses

Philip King, Ph.D.

Professor of Microbiology and Immunology
kingp@umich.edu
Research Interests:

Intracellular signaling pathways controlling T lymphocyte activation, differentiation and death. Lymphatic vessel biology, cancer and angiogenesis

Ilona Kryczek, Ph.D.

Research Assistant Professor of Surgery
ilonak@umich.edu
Research Interests:

Tumor immunoediting, Inflamation, Human immunology

Steven L. Kunkel, Ph.D.

Senior Associate Dean for Research
Endowed Professor, Department of Pathology
slkunkel@umich.edu
Accepting Students
Research Interests:

Epigenetics, chemokine and cytokine biology
 

Yasmina Laouar, Ph.D.

Associate Professor of Microbiology and Immunology
ylaouar@umich.edu
Accepting Students
Research Interests:

Immunology/Mechanisms of Immunosuppression

Yu Leo Lei, D.D.S., Ph.D.

Assistant Professor of Dentistry, Dept. of Periodontics and Oral Medicine
Assistant Professor of Otolaryngology- Head and Neck Surgery
U-M Comprehensive Cancer Center
leiyuleo@umich.edu
Accepting Students
Research Interests:

Innate Immunity, Tumor Immunology, Oral Head & Neck Cancer, Autophagy, NLR proteins, Proteomics and CRISPR/Cas9 systems

Qiao Li, Ph.D.

Research Associate Professor of Surgery
qiaoli@umich.edu
Accepting Students
Research Interests:

Development of cancer immunotherapy using immune cells, such as T cells,
B cells and dendritic cells (DCs). Use of in vivo primed and in vitro activated effector T and B cells for cancer treatment, and generate DC-based cancer stem cell vaccines to target cancer stem cells

Pedro Lowenstein, M.D., Ph.D.

Richard C. Schneider Professor of Neurosurgery
Professor of Cell and Developmental Biology
pedrol@umich.edu
Accepting Students
Research Interests:
His research program is composed of four themes: (i) studies on innate immune responses to brain tumors; (ii) studies on the mechanisms by which the co-deletion of 1p/19q increases the sensitivity of low grade brain tumors to chemo- and radiotherapy; (iii) studies on the self-organization of brain tumors, especially one of its main
...

Nicholas Lukacs, Ph.D.

Godfrey Dorr Stobbe Professor of Research
Professor of Pathology
Assistant Dean for Research Faculty
nlukacs@umich.edu
Accepting Students
Research Interests:

Pulmonary immune responses to allergens and viral infections. Role of cytokines and chemokines

Gary Luker, M.D.

Associate Professor of Radiology
Associate Professor of Microbiology & Immunology
Associate Professor of Biomedical Engineering
gluker@umich.edu
Research Interests:

Chemokines and chemokine receptor signaling in cancer; molecular imaging

Carey Lumeng, M.D., Ph.D.

Associate Professor of Internal Medicine, Division of Pediatrics and Communicable Diseases
Associate Professor, Molecular and Integrative Physiology
clumeng@umich.edu
Accepting Students
Research Interests:

Obesity and Inflammation.  Adipose tissue macrophages and lymphocyte activation with obesity.  Dietary influences on inflammatory cell activation. Intravital microscopy on adipose tissue leukocytes

Steven K. Lundy, Ph.D.

Research Associate Professor of Internal Medicine, Division of Rheumatology
sklundy@umich.edu
Accepting Students
Research Interests:

Regulation of the immune system in autoimmunity, asthma, cancer and infections by B lymphocytes

Costas Lyssiotis, PhD

Assistant Professor of Molecular and Integrative Physiology
clyssiot@med.umich.edu
Accepting Students

Peter Mancuso, Ph.D.

Associate Professor, Department of Environmental Health Sciences
pmancuso@umich.edu
Research Interests:

Regulation of the innate immune response against bacterial pneumonia, Role of the eicosanoids and their receptors in pneumococcal pneumonia, Impact of second hand tobacco smoke in lung disease, Role of adiponectin and leptin in inflammation and infection in obesity

Yang Mao-Draayer, M.D., Ph.D.

Associate Professor of Neurology, Multiple Sclerosis Center/ Holtom-Garrett Neuroimmunology Program
maodraay@umich.edu
Accepting Students
Research Interests:

Neuroimmunology; the Interplay between immune system and neural stem/progenitor cells in multiple sclerosis (MS); cytokine, neurotrophin production and neuroprotective mechanisms for neuroregeneration in MS. The mission is to enhance translational research by bridging basic research in neuroimmunology with human studies in MS

David Markovitz, M.D.

Professor of Internal Medicine, Division of Infectious Diseases
dmarkov@umich.edu
Research Interests:

The role of DEK in cancer and autoimmunity; the role of vimentin in the immune response; endogenous retroviruses; development of antiviral agents

James Moon , PhD

John Gideon Searle Assistant Professor
Department of Pharmaceutical Sciences
Department of Biomedical Engineering
moonjj@umich.edu
Accepting Students
Research Interests:

Vaccine delivery and Cancer immunotherapy

Thomas Moore, Ph.D.

Research Assistant Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
Director, U.M. Flow Cytometry Core Facility
tmoore@umich.edu
Research Interests:

Innate host responses during bacterial infection, microbial pathogenesis, T cells and bacterial infection

Gabriel Nunez, M.D.

Paul de Kruif Endowed Professor of Pathology
bclx@umich.edu
Research Interests:

Nod-like receptors; Host defense against bacterial pathogens; Mucosal Immunity; Role of the microbiota in immunity and pathogen eradication; Inflammatory disease; inflammation and cancer

Asma Nusrat, M.D.

Aldred S. Warthin Professor, Director of Experimental Pathology
anusrat@umich.edu
Accepting Students
Research Interests:
Clinical Subspecialty: Gastrointestinal and Hepatobiliary Pathology
Research Subspecialty: Mucosal Inflammation and Epithelial Pathobiology

Mary O'Riordan, Ph.D.

Associate Professor of Microbiology & Immunology
Associate Dean of Graduate & Postdoctoral Studies
oriordan@umich.edu
Accepting Students
Research Interests:

Innate immunity to intracellular bacterial pathogens

Michal Olszewski, D.V.M., Ph.D.

Research Biologist, Veteran Affairs Ann Arbor Healthcare System
Associate Professor of Internal Medicine, Pulmonary and Critical Care Division
olszewsm@umich.edu
Accepting Students
Research Interests:

Interface of the adaptive and innate immunity during host-pathogen interactions

John Osterholzer, M.D.

Associate Professor of Internal Medicine, Pulmonary and Critical Care Division
Veteran Affairs Ann Arbor Healthcare System
oster@umich.edu
Research Interests:

Investigating the recruitment and function of myeloid cells (monocytes, dendritic cells, and macrophages) that accumulate in the lung in response to infection and/or injury

Charles Parkos, M.D., Ph.D.

Carl V. Weller Professor and Chair, Mucosal Inflammation and Epithelial Pathobiology, Dept. of Pathology
cparkos@umich.edu
Accepting Students
Research Interests:

Mucosal Inflammation and Epithelial Pathobiology
Gastrointestinal PathologyHepatobiliary Pathology

Marc Peters-Golden, M.D.

Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
petersm@umich.edu
Accepting Students
Research Interests:

 

Cell and molecular regulation of macrophage biology in inflammation, innate immunity, and fibrosis of the lung

 

Sem Phan, Ph.D, M.D.

Professor of Pathology
shphan@umich.edu
Accepting Students
Research Interests:

Inflammatory/immune responses and tissue injury and repair

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