Faculty

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(Includes Name, Title, Research Interests, Techniques)

Ulus Atasoy, M.D., M.A.

Associate Professor, Department of Internal Medicine, Division of Allergy and Clinical Immunology
Chief of Allergy-Immunology, Ann Arbor VA
atasoyu@med.umich.edu
Accepting Students
Research Interests:

- Posttranscriptional gene regulation in lung inflammation and cancer - RNA biology - Asthma and allergy - The role of the RNA binding protein HuR in 1) allergen induced airway inflammation, and 2) helper T cell differentiation and function

Shannon Carty, MD

Assistant Professor of Internal Medicine, Division of Hematology/Oncology
scarty@umich.edu
Accepting Students
Research Interests:

T cell immunobiology, Epigenetics

Marilia Cascalho, M.D., Ph.D.

Associate Professor of Surgery, Microbiology & Immunology
marilia@umich.edu
Accepting Students
Research Interests:
The Cascalho and Platt laboratories investigates immunity to mutable microbes, transplants and tumors.
 

Maria Castro, PhD

R.C. Schneider Collegiate Professor of Neurosurgery
Professor of Cell and Developmental Biology
mariacas@umich.edu
Accepting Students
Research Interests:
Pediatric and adult brain cancer biology and therapeutics. Epigenetics, cancer metabolism, and signaling networks that mediate tumor progression. Uncovering the role of secreted cancer ligands in hematopoietic stem cell development and anti-tumor immunity. Nanotechnology to develop novel anti-cancer therapies. DNA damage, DNA damage response,
...

Cheong-Hee Chang, Ph.D.

Professor of Microbiology and Immunology
heechang@umich.edu
Accepting Students
Research Interests:

Regulation of innate-like CD4 T cell development and function

Grace Chen, M.D., Ph.D.

Associate Professor of Internal Medicine, Division of Hematology/Oncology
gchenry@umich.edu
Accepting Students
Research Interests:

Inflammation and cancer; role of gut microbiota and Nod-like receptors in colitis and cancer

Clifford Cho, MD

C. Gardner Child Professor of Surgery
cliffcho@med.umich.edu
Accepting Students
Research Interests:

Our laboratory is interested in finding new ways to optimize CD8+ T cell-based approaches to cancer immunotherapy. Projects under active investigation include an exploration of the immunostimulatory effects of a novel form of tumor ablation called histotripsy, and the investigation of the impact of effector and memory CD8+ T cells on cancer stem cells.

Kathleen Collins, M.D., Ph.D.

Professor of Internal Medicine
Professor of Microbiology and Immunology
klcollin@umich.edu
Accepting Students
Research Interests:
The Collins lab focuses on understanding the molecular mechanisms by which virally infected cells establish a persistent infection; we use patient samples to determine which cells form clinically significant reservoirs and to develop strategies to eradicate them. A major focus of the Collins laboratory has been on understanding the role of
...

Jeffrey Curtis, MD

Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
jlcurtis@umich.edu
Accepting Students
Research Interests:

Lung immunity in humans and mice. 
Specifically: immunopathogenesis of COPD; Efferocytosis; Interactions of lung leukocytes with the lung microbiome. 

Jane Deng, MD, MS

Associate Professor of Internal Medicine
Section Chief Pulmonary VA Ann Arbor
jcdeng@med.umich.edu
Accepting Students
Research Interests:

Pulmonary host defense against influenza and bacterial infections of the lung Role of microbiome on regulation of immune responses Neutrophil phenotypes during infection

David Fox, M.D.

Professor, Department of Internal Medicine
Chief, Division of Rheumatology
dfox@umich.edu
Research Interests:

Human T lymphocyte biology, rheumatoid arthritis, T cell interactions with synovial cells, regulation of TH17 cells

Christine Freeman, PhD

Research Assistant Professor, Internal Medicine, Division of Pulmonary and Critical Care Medicine
cmfreema@umich.edu
Accepting Students
Research Interests:

Role of Toll-like receptors on CD8+ and CD4+ T cells and NK cells in regards to chronic obstructive pulmonary disease; Immunopathogenesis of chronic obstructive pulmonary disease. 

Katherine Gallagher, MD

Associate Professor of Surgery, Section of Vascular Surgery
Associate Professor Microbiology and Immunology
kgallag@umich.edu
Accepting Students
Research Interests:

I have had a long-standing defined clinical and translational interest in the mechanisms underlying impaired diabetic wound healing. My long-term goal is to uncover the basic mechanisms responsible for the coordination of immune cells in early tissue repair processes, determine impairments in Type 2 Diabetes and translate this knowledge to the bedside.

Daniel Goldstein, MD

Eliza Maria Mosher Collegiate Professor in Internal Medicine
Research Professor, Institute of Gerontology
Director, Michigan Biology of Cardiovascular Aging
drgoldst@umich.edu
Research Interests:

The overall theme of Dr. Goldstein’s laboratory is how inflammation impacts different disease states. Broadly, Dr. Goldstein’s laboratory investigates the importance of inflammation in organ transplantation, and in aging

Irina Grigorova, PhD

Associate Professor of Microbiology and Immunology (effective Sept. 2019)
igrigor@umich.edu
Research Interests:

regulation of T-dependent B cell response, control of auto-reactive B cells

Johann Gudjonsson, M.D., Ph.D.

Arthur C. Curtis Professor of Skin Molecular Immunology
Associate Professor, Dermatology
Frances and Kenneth Eisenberg Emerging Scholar
johanng@med.umich.edu
Accepting Students
Research Interests:
Immunology, genetics, bioinformatics
 

Simon Hogan, PhD

ASKWITH RESEARCH PROFESSOR OF FOOD ALLERGY AND PROFESSOR OF PATHOLOGY
sihogan@med.umich.edu
Research Interests:

innate immunity, epithelia, food allergy, Inflammatory Bowel Diseases, eosinophilic esophagitis

Joseph Holoshitz, M.D.

Professor of Internal Medicine, Division of Rheumatology
Associate Chief for Research
jholo@umich.edu
Accepting Students
Research Interests:

Signal transduction, small molecules and immunomodulatory peptides in autoimmunity; Gene-environment interaction in autoimmunity;Molecular mechanisms of MHC-disease association

Gary Huffnagle, PhD

Nina and Jerry D Luptak Professor of Food Allergy
Associate Chair for Undergraduate Studies, MCDB
Professor, Molecular, Cellular and Developmental Biology (MCDB)
Professor, Pulmonary & Critical Care Medicine
Research Professor, Mary H Weiser Food Allergy Center
Professor, Microbiology and Immunology
Interim Co-Director of the Graduate Program in Immunology
ghuff@umich.edu
Accepting Students
Research Interests:

The microbiome & respiratory diseases; the mucosal immunobiology and microbiology of food allergies; and the microbiology, immunology and microbial ecology of the yeast Candida albicans.

David Irani, M.D.

Associate Professor of Neurology, Holtom-Garrett Program in Neuroimmunology
davidira@umich.edu
Research Interests:

Neuroimmunology; immunopathogenesis of viral infections of the central nervous system; innate immunity to viruses; immune mechanisms of neuronal and glial cell injury

J. Michelle Kahlenberg, M.D., Ph.D.

Associate Professor of Internal Medicine, Division of Rheumatology
mkahlenb@umich.edu
Accepting Students
Research Interests:
Innate Immune Disturbances in Systemic Lupus Erythematosus, Ultraviolet Light responses in the skin in healthy and lupus patients and mice, microbiome differences in the skin of lupus patients, interferon signaling, interferon kappa biology in keratinocytes
...

Nobuhiko Kamada, Ph.D.

Assistant Professor of Internal Medicine, Division of Gastroenterology
nkamada@med.umich.edu
Accepting Students
Research Interests:

Mucosal Immunology in gastrointestinal tract: host-microbial interaction in the pathogenesis of inflammatory bowel disease.

Venkat Keshamouni, Ph.D.

Associate Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
vkeshamo@umich.edu
Research Interests:

Cancer cell and host immune cell interactions in tumor microenvironment; Tumor tolerance mechanisms; TGF-b and TLR signaling

Chang Kim, PhD

Professor of Pathology
Kenneth and Judy Betz Family Endowed Professor
Mary H. Weiser Food Allergy Center
Experimental Pathology, Department of Pathology
chhkim@med.umich.edu
Accepting Students
Research Interests:

1. Cell trafficking and function in the hematolymphoid system. We study trafficking mechanisms of lymphocytes for development and effector functions. Special emphasis is on the roles of chemokine receptors and integrins in regulating the trafficking of various T cell populations (Th17, Th9, Th1, Tfh, Tfr, IL-10+ T cells, and FoxP3+ Tregs) and innate lymphoid cells (ILCs).

2. Mucosal immunity, inflammation, and cancer. Balanced immunity is important for prevention of inflammation and cancer. We study the interactive relationships among immunity, inflammation and cancer development in...

Philip King, PhD

Professor of Microbiology and Immunology
kingp@umich.edu
Research Interests:

Intracellular signaling pathways controlling T lymphocyte activation, differentiation and death. Lymphatic vessel biology, cancer and angiogenesis

Ilona Kryczek, Ph.D.

Research Assistant Professor of Surgery
ilonak@umich.edu
Research Interests:

Tumor immunoediting, Inflamation, Human immunology

Steven L. Kunkel, PhD

Interim Chief Scientific Officer, Michigan Medicine
Interim Executive Vice Dean for Research, Medical School
Senior Associate Dean for Research
Endowed Professor in Pathology Research
Peter A. Ward Distinguished University Professor
slkunkel@umich.edu
Research Interests:

Epigenetics, chemokine and cytokine biology
 

Yasmina Laouar, Ph.D.

Associate Professor of Microbiology and Immunology
ylaouar@umich.edu
Accepting Students
Research Interests:

Immunology/Mechanisms of Immunosuppression

Yu Leo Lei, D.D.S., Ph.D.

Assistant Professor of Dentistry, Dept. of Periodontics and Oral Medicine
Assistant Professor of Otolaryngology- Head and Neck Surgery
U-M Comprehensive Cancer Center
leiyuleo@umich.edu
Accepting Students
Research Interests:

Cancer Immunotherapy, Cancer Immune Escape, Immune Engineering

Qiao Li, Ph.D.

Research Associate Professor of Surgery
qiaoli@umich.edu
Accepting Students
Research Interests:

Development of cancer immunotherapy using immune cells, such as T cells,
B cells and dendritic cells (DCs). Use of in vivo primed and in vitro activated effector T and B cells for cancer treatment, and generate DC-based cancer stem cell vaccines to target cancer stem cells

Pedro Lowenstein, MD, PhD

Richard C. Schneider Professor of Neurosurgery
Professor of Cell and Developmental Biology
pedrol@umich.edu
Accepting Students
Research Interests:
His research program is composed of four themes: (i) studies on innate immune responses to brain tumors; (ii) studies on the mechanisms by which the co-deletion of 1p/19q increases the sensitivity of low grade brain tumors to chemo- and radiotherapy; (iii) studies on the self-organization of brain tumors, especially one of its main
...

Nicholas Lukacs, PhD

Godfrey Dorr Stobbe Professor of Research Pathology
Scientific Director, Mary H. Weiser Food Allergy Center
nlukacs@umich.edu
Accepting Students
Research Interests:

Pulmonary immune responses to allergens and viral infections. Role of cytokines and chemokines

Gary Luker, MD

Professor of Radiology, Biomedical Engineering, and Microbiology & Immunology
gluker@umich.edu
Research Interests:

Computational imaging in cancer biology and therapy

Carey Lumeng, M.D., Ph.D.

Associate Professor of Internal Medicine, Division of Pediatrics and Communicable Diseases
Associate Professor, Molecular and Integrative Physiology
clumeng@umich.edu
Accepting Students
Research Interests:

Obesity and Inflammation.  Adipose tissue macrophages and lymphocyte activation with obesity.  Dietary influences on inflammatory cell activation. Intravital microscopy on adipose tissue leukocytes

Costas Lyssiotis, PhD

Assistant Professor of Molecular and Integrative Physiology
clyssiot@med.umich.edu
Accepting Students
Research Interests:

Tumor Metabolism, Cancer, Pancreatic Cancer, Immunometabolism, Metabolomics, Autoimmunity

Peter Mancuso, PhD

Associate Professor, Department of Nutritional Sciences, School of Public Health
pmancuso@umich.edu
Accepting Students
Research Interests:

Impact of adipokines and metabolic disease on innate immunity and host defense against bacterial pneumonia

Yang Mao-Draayer, M.D., Ph.D.

Professor of Neurology, Multiple Sclerosis Center/ Holtom-Garrett Neuroimmunology Program
maodraay@umich.edu
Accepting Students
Research Interests:

Neuroimmunology; the Interplay between immune system and neural stem/progenitor cells in multiple sclerosis (MS); cytokine, neurotrophin production and neuroprotective mechanisms for neuroregeneration in MS. The mission is to enhance translational research by bridging basic research in neuroimmunology with human studies in MS

David Markovitz, M.D.

Professor of Internal Medicine, Division of Infectious Diseases
dmarkov@umich.edu
Research Interests:

The Markovitz laboratory focuses on understanding how human cellular factors control the replication of viruses, and retroviruses in particular. These studies are performed both to understand the biology of viruses and to develop possible therapies for these important human pathogens, as well as to exploit the viruses as a mechanism for understanding human cellular biology.

James Moon , PhD

John Gideon Searle Associate Professor
Department of Pharmaceutical Sciences
Department of Biomedical Engineering
moonjj@umich.edu
Accepting Students
Research Interests:

Vaccine delivery and Cancer immunotherapy

Bethany Moore, PhD

Professor and Interim Chair, Department of Microbiology and Immunology
Galen B. Toews Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
bmoore@umich.edu
Accepting Students
Research Interests:

mucosal immunology, pathogenesis of lung fibrosis, herpesviral and bacterial infections post-stem cell transplant, bacterial superinfection post-influenza, diabetic wound healing

Gabriel Nuñez, MD

Paul de Kruif Endowed Professor of Pathology
bclx@umich.edu
Research Interests:

Nod-like receptors; Host defense against bacterial pathogens; Mucosal Immunity; Role of the microbiota in immunity and pathogen eradication; Inflammatory disease; inflammation and cancer

Asma Nusrat, M.D.

Aldred S. Warthin Professor, Director of Experimental Pathology
anusrat@umich.edu
Accepting Students
Research Interests:
Clinical Subspecialty: Gastrointestinal and Hepatobiliary Pathology
Research Subspecialty: Mucosal Inflammation and Epithelial Pathobiology

Mary O'Riordan, Ph.D.

Frederick C. Neidhardt Collegiate Professor
Professor of Microbiology and Immunology
Associate Dean of Graduate & Postdoctoral Studies
oriordan@umich.edu
Research Interests:

Innate immunity to intracellular bacterial pathogens

Michal Olszewski, DVM, PhD

Research Biologist, Veteran Affairs Ann Arbor Healthcare System
Associate Professor of Internal Medicine, Pulmonary and Critical Care Division
olszewsm@umich.edu
Accepting Students
Research Interests:

Over the last 15 years, my studies have primarily focused on host-pathogen interactions between the invasive fungus C. neoformans and the mammalian immune system.Specifically, we look into the mechanisms involved in the pathogenesis of Cryptococcus neoformans infection and the persistence of this microbe. Our studies also seek to understand both the effects of immunomodulation on host antifungal defenses and mechanisms of immune evasion exhibited by fungi, as well as to explore pre-clinical approaches of immuno-modulatory therapies.

John Osterholzer, M.D.

Associate Professor of Internal Medicine, Pulmonary and Critical Care Division
Veteran Affairs Ann Arbor Healthcare System
oster@umich.edu
Research Interests:

Host defense against fungal lung infection; Biology of lung myeloid cells including monocytes, dendritic cells, and macrophages; Contribution of lung myeloid cells to lung fibrogenesis in response to airway and alveolar epithelial cell injury; Pathogenesis of deployment-related lung disease.

Charles Parkos, MD, PhD

Carl V. Weller Professor and Chair, Mucosal Inflammation and Epithelial Pathobiology, Dept. of Pathology
cparkos@umich.edu
Accepting Students
Research Interests:

Mucosal Inflammation and Epithelial Pathobiology
Gastrointestinal PathologyHepatobiliary Pathology

Marc Peters-Golden, MD

Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
petersm@umich.edu
Research Interests:

 Cell and molecular regulation of macrophage biology in inflammation, innate immunity, and fibrosis of the lung

 

Sem Phan, Ph.D, M.D.

Professor of Pathology
shphan@umich.edu
Accepting Students
Research Interests:

Inflammatory/immune responses and tissue injury and repair

Jeffrey Platt, M.D., Ph.D.

Professor of Surgery
Professor of Microbiology and Immunology
plattjl@umich.edu
Research Interests:

Transplantation immunology, accommodation, immunologic properties and genomic stability of stem cells, genetic basis of cell transformation and oncogenesis

Antonia Popova, MD

Assistant Professor, Department of Pediatrics and Communicable Diseases
Division of Pediatric Pulmonology
antoniap@med.umich.edu
Accepting Students
Research Interests:
The focus of our laboratory is on pulmonary complications of premature birth. These complications include bronchopulmonary dysplasia (BPD), a chronic lung disease of prematurely-born infants in which lung alveoli fail to form normally, and asthma.
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