Jonathan Roussey, PhD

Research Fellow, Internal Medicine - Division of Pulmonary and Critical Care Medicine

Biography

I received my B.S. in Biochemistry from the University of Michigan - Dearborn in 2009, and my Ph.D. in Comparative Medicine and Integrative Biology from Michigan State University in 2015.

Research Interests

I am investigating the role of T cells (especially helper and regulatory) and the PD-L1/PD-L2/PD-1 signaling axis in the modulation of immune responses to pulmonary infection with Cryptococcus neoformans in mice.

Techniques

Flow cytometry, histology, cell culture, cell sorting, microscopy, confocal microscopy, large animal necropsy, small animal necropsy, rodent survival surgery, PCR, qPCR, nucleic acid extraction, general molecular biology.

Publications

1. Roussey, J.A., Oliveira, L.J., Langohr, I.M., Sledge, D.G., Coussens, P.M., (2015). Regulatory T cells and immune profiling in Johne’s disease lesions. Veterinary Immunology and Immunopathology. Submitted.

2. Everman, J.L., Eckstein, T.M., Roussey, J.A., Coussens, P.M., Bannantine, J.P., Bermudez, L.E., (2014). Identification and characterization of the inflammatory phenotype of Mycobacterium avium subspecies paratuberculosis using a novel in vitro cell culture passage model, Microbiology, doi: 10.1099/mic.0.000106.

3. Roussey, J.A., Steibel, J.P., Coussens, P.M., (2014). Regulatory T cell activity and signs of T cell unresponsiveness in bovine paratuberculosis, Front Vet Sci, 1:20.

4. Rosa, F.B., Roussey, J., Coussens, P.M., Langohr I.M., (2013). Pathology in practice: Johne’s disease, J Am Vet Med Assoc, 242(12):1655-7.

5. Coussens, P.M., Sipkovsky, S., Murphy, B., Roussey, J., Colvin, C.J., (2012). Regulatory T cells and their potential role in bovine paratuberculosis, Comp Immunol Microbiol Infect Dis, 35(3):233-9.

Immunology Mentor